Caracterization of patients hospitalized for sickle cell crisis

A case series at a Bogotá hospital

Abstract

Introduction: sickle cell anemia (SCA) is a hereditary hemoglobinopathy that fosters vaso-occlusive episodes and chronic hemolysis, among other complications, representing a frequent cause of hospitalization and morbidity. There is limited clinical and epidemiological information on adult patients hospitalized for sickle cell crises in Colombia, especially in Bogotá.

Objective: to characterize the demographic, clinical, and paraclinical variables and outcomes of patients hospitalized for sickle cell crises at a university hospital in Bogotá.

Methods: this was a retrospective, observational case series study.

Participants: patients age 18 and above who were hospitalized for a sickle cell crisis.

Results: eight patients were included. The most frequent reason for admission was pain associated with vaso-occlusive crises. The most common prior conditions were chronic pain and avascular osteonecrosis. Laboratory tests showed anemia with elevated hemolysis markers. Most patients required opioid treatment and simple transfusions, with a positive course in all cases.

Conclusions: The clinical and paraclinical characteristics of patients hospitalized for SCA crises aligned with those described in the international literature, with a favorable clinical outcome using standard treatment. These findings provide relevant local information and highlight the need to strengthen comprehensive care and follow-up strategies in this population