Hypothyroidism
Strategies to optimise control and improve clinical results
Abstract
Introduction: After diabetes mellitus, hypothyroidism is the most prevalent endocrine disorder, particularly among women, with significant impact on cardiovascular and metabolic health as well as quality of life. Thyroid-stimulating hormone (TSH) is the most sensitive biomarker for diagnosis and follow-up.
Objective: To review the scientific evidence and practical strategies for optimizing TSH control in patients with hypothyroidism.
Methods: Narrative review of the published literature, complemented by expert insights derived from the conference “Hypothyroidism: Keys to Maintaining TSH Within Target Ranges” during the Third Latin American Women’s Summit, July 31–August 2, 2025, in Barranquilla, Colombia.
Results: A large proportion of patients with hypothyroidism remain outside the recommended therapeutic TSH targets. Both suppressed and elevated TSH levels are associated with increased cardiovascular mortality, with risk proportional to the degree of deviation from the normal range. Factors such as adherence, absorption, and drug interactions influence outcomes.
Conclusion: The management of hypothyroidism should be individualized, integrating strategies that promote adherence and regular monitoring to ensure optimal TSH control.
Copyright (c) 2025 Nuvia Batista-Rujano, Katiana Castillo Martin
This work is licensed under a Creative Commons Attribution 4.0 International License.
Acta Medica Colombiana uses the CC-BY 4.0 license. Authors retain all rights over their work.
